New York- OCSAR-winning actress Tatum O’Neal went on a liquor-fueled lesbian rampage Wednesday night at Meatpacking District hot spot Pop Burger.

At about midnight, O’Neal, 41, daughter of Ryan O’Neal and ex-wife of John McEnroe, walked into the hipster restaurant/lounge, which had been visited by the likes of Billy Baldwin, Natasha Henstridge and Alessandra Ambrosio earlier in the evening. O’Neal ambled up to the bar and started ordering cosmopolitans – apparently not her first libations of the evening.

She wasn’t there very long when she spilled a drink all over a fellow customer, and instead of acknowledging the gaffe, strolled outside to smoke a cigarette.

While managers placated the soggy patron with free cocktails, O’Neal started chatting up a pretty, blond 30-ish woman she met outside. O’Neal invited her new friend inside for a drink – and then the fun began.

“They started fooling around and were full-on making out,” a spywitness told PAGE SIX’s Jared Paul Stern. “Then she started feeling the girl’s boobs and rubbing her crotch. It got so graphic that the manager had to keep sending a waiter to the table to tell them to stop because they were causing a scene.”

The entire crowd gawked at the steamy sapphic embrace, and finally O’Neal and her lusty lady paid the check and got up and left the lounge together holding hands.

O’Neal’s rep did not return calls.

Pop Burger owner Roy Liebenthal stated, “We never comment on the private lives of our customers, ever.”

Something about star-studded Pop Burger seems to inspire outrageous behavior. Last November, we reported that porn star Savanna Samson went wild there one night, flashing the crowd, groping a busboy and hitting on several eager males.

Last fall, O’Neal, who has been to rehab in the past, published a provocative memoir, “A Paper Life,” in which she described McEnroe as a self-absorbed pothead and depicted her father as an emotionally abusive, hard-partying playboy.

O’Neal recounted in the book how she turned to cocaine and heroin to cope with feelings of low self-esteem and revealed that when she was 12, she confronted her dad about sleeping with her friend, Melanie Griffith, then 18. Her father called her allegations “malicious lies.”